Disable from Outlook Connect / Connect for Office / Offline through out the Organization.
There can be situations when your customers want to disable Outlook Connect / Connect for Office / Offline through out their Organization.
You can do this by switching off Desktop Integration Clients all profiles in the organization.
Step 1: Setup | Administration Setup | Manage Users | Profiles
Step 2: Click on a profile
Step 3: Click the edit button
Step 4: Scroll down to the "Desktop Integration Clients" section
Step 5: Choose the Desktop client/clients you would like to disable (Outlook Connect / Connect for Office / Offline)
Step 6: Set "Off (access denied)" as the value of the picklist for the Desktop client of your interest
Step 7: Click Save button
Repeat step 2 to 7 for all the profiles that you want to disable one or more of the desktop clients.