It is possible for System Administrators to create custom Home Page Layouts, and assign the layouts to users based on their user profile.
Note: If you are selecting a Dashboard Component on your Home Page Layout, the users that are assigned the layout will need to have at least read access to a Dashboard folder in order to view the component. The first row of the Dashboard will be displayed on the Home Page.
See also
Design Home Page Layouts in Salesforce Classic
Set Up the Lightning Experience Home Page
Lightning App Builder
Users Cannot See Home Page Tab
Customize the Home Page
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