Changing the Salesforce System User or disconnecting and reconnecting to the same or a different Agentforce Sales (formerly Sales Cloud) or Agentforce Service (formerly Service Cloud) org will have an impact on your Marketing Cloud Connect implementation. To change the Salesforce System User you will have to disconnect and reconnect. Please use this article if you are trying to change the Marketing cloud API user.
How to find details of Salesforce System User?
Go to Marketing Cloud> Setup> Apps> Salesforce Integration.
How to find the MC API user?
Login using Salesforce System User> App Launcher> Marketing Cloud? Marketing Cloud Connect Settings
Impacts of Disconnecting:
Please check this article for more information on disconnect impact. Other impacts that could be experienced include:
Post Reconnection Impact:
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